产地：Bilmol
货号：BML-CA409-0050
规格：50 ug
名称：Xestospongin C
CAS: 88903-69-9
代替产品：ALX-350-382
Product Specification
Formula: C28H50N2O2
MW: 446.7
Purity: ≥90%
Appearance: White to off-white powder
Source/Host: Isolated from an Okinawan marine sponge Xestospongia sp.
Solubility: Soluble in DMSO or 100% ethanol
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
Handling: Packaged under inert gas.
Protect from light.
Replaces Prod. #: ALX-350-382
Xestonspongin C is a structurally novel marine alkaloid isolated from the Okinawan sponge Xestospongia sp. It is a potent, cell-permeable inhibitor of IP3 receptor-mediated Ca2+ release (IC50 = 358 nM). However, since xestospongin C also inhibits voltage-dependent Ca2+ and K+ currents at concentrations similar to those which inhibit the IP3 receptor, it can only be regarded as a selective blocker of the IP3 receptor in permeabilized ells and not in cells with intact plasma membranes.
Has vasodilatory properties.