Bongkrekic acid is an inhibitory ligand of the mitochondrial adenine nucleotide translocase. It inhibits mitochondrial permeability transition pore opening. At 50 µM it inhibits dexamethasone- apoptosis in thymocytes, preventing the PARP cleavage and DEVDase (caspase-3 like) activity normally produced by these treatments.
Product Specification
Formula: C28H38O7 * 3NH3
MW: 531.7
Purity: ≥98%
Appearance: Lypophilized solid
CAS: 11076-19-0
Reconstitution: Reconstitute to 1mg/ml with distilled water
Shipping: AMBIENT
Long Term Storage: -20°C