Replaces Prod. #: ALX-480-060
SQ 22536 is a cell-permeable adenylate cyclase inhibitor. It inhibits cAMP production induced by prostaglandin E1 in platelet lysates (IC50=82 µM) and in intact platelets (IC50=1 µM). It has been successfully employed as a probe for the involvement of adenylate cyclase in a variety of receptor systems including those for prostaglandins and neurotransmitters. ReducesPGE2-induced inhibition of O2- production.
Product Specification
Formula: C9H11N5O
MW: 205.2
Purity: 99% (TLC)
Appearance: White to off-white solid
CAS: 17318-31-9
Solubility: Soluble in water (25mg/l) or DMSO
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Stock solutions are stable for up to 3 months at -20°C.