Replaces Prod. #: ALX-340-032
Analog of anandamide (Prod. No. BML-FA017). Potentiates the activity of endogenous anandamide by blocking its re-uptake into presynaptic membranes. Activates TRPV1 (EC50=0.04µM) at concentrations lower than those required to inhibit anandamide transport into the cell (neuronal (C6 glioma cells): IC50=10µM; non-neuronal (rat RBL-2H3 cells): IC50=11µM). Low affinity to FAAH (IC50=5.9µM), to CB1 receptor (IC50=1.76µM) and to CB2 receptor (IC50>1µM).
Product Specification
Alternative Name: N-(4-Hydroxyphenyl)-5Z,8Z,11Z-eicosatetraenamide, N-(4-Hydroxyphenyl)arachidonoylamide
Formula: C26H37NO2
MW: 395.6
Purity: ≥98% (TLC)
Appearance: Waxy solid.
CAS: 198022-70-7
Solubility: Soluble in DMSO (>25mg/ml) or 100% ethanol (>25mg/ml).
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
Use/Stability: Stable for up to one year after receipt when stored at -20°C. Solutions are stable for up to 3 months when stored at -20°C under an inert atmosphere of nitrogen or argon.
Handling: Keep under inert gas.
Protect from air.