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DRB is a potent and specific inhibitor of casein kinase II (CKII, IC50~6 µM). It has been used to inhibit RNA polymerase II mediated-transcription which may be dependent on CKII and its interaction with ATF-1.
Product Specification
Alternative Name: DRB, 5,6-Dichlorobenzimidazole riboside
Formula: C12H12Cl2N2O4
MW: 319.1
Purity: 98%
Appearance: White solid.
CAS: 53-85-0
Solubility: Soluble in DMSO (20mg/ml), 100% ethanol, and dimethyl formamide (100mM).
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.