耗材描述
产地:Biomol
货号:BML-G237-0005
规格:5 mg
名称:Cerulenin
保存温度:-20°C
Antibiotic. Fatty acid synthase (FAS) inhibitor reported to bind in equimolar ratio to β-keto-acyl-ACP synthase (KAS; IC50=1.5µM), thus inhibiting protein acylation at concentrations of 45-134 µM. Produces metabolic effects similar to the effects of leptin, but through mechanisms that are independent of, or down-stream from, both leptin and melanocortin receptors. Apoptosis inducer. Inhibitor of bacterial fatty acid synthesis (inhibits FabH, FabB and FabF condensation enzymes).
Product Specification
Alternative Name: 2,3-Epoxy-4-oxo-7,10-dodecadienamide
Formula: C12H17NO3
MW: 223.3
Purity: ≥98% (TLC)
Appearance: White to off-white solid.
CAS: 17397-89-6
MI: 14: 2004
RTECS: JR1670000
Solubility: Soluble in DMSO (>10mg/ml) or 100% ethanol (>10mg/ml).
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Hazard: HARMFUL.