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Novel DNA topoisomerase I inhibitor. Unlike camptothecin, β-lapachone does not stabilize the cleavable complex, indicating a novel mode of action. Induces apoptosis in HL-60 and human prostate cancer cells via a p53-independent mechanism and blocks the cell cycle at G0/G1.
Product Specification
MW: 242.4
Purity: 98%
CAS: 4707-32-8
Shipping: AMBIENT
Long Term Storage: -20°C