产地:Biomol
货号:BML-KC162-0010
规格:10 ug
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快来www.haoranbio.com体验在线订购给您带来的快捷和方便吧! Iberiotoxin is a recombinant peptide expressed in and purified from E. coli. Iberiotoxin was originally isolated from the scorpion Mesobuthus tamulus and was shown to block large conductance Ca2+ activated K+ channels in smooth muscle cells. Later it was shown to specifically block KCa1.1 (Slo) channels with Ki of about 1nM. In addition, experiments with cloned KCa1.1 channels demonstrate the strong effect of the slob subunits on the potency of block by Iberiotoxin.
Product Specification
Alternative Name: IbTx
MW: 4230.0
Purity: ≥ 98%
Appearance: Lyophilized solid.
Sequence: Glu-Phe-Thr-Asp-Val-Asp-Cys-Ser-Val-Ser-Lys-Glu-Cys-Trp-Ser-Val-Cys-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys-Met-Gly-Lys-Lys-Cys-Arg-Cys-Tyr-Gln
CAS: 129203-60-7
Solubility: Soluble in Water.
Reconstitution: Each vial contains 10µg of unbuffered protein and is provided as lyophilized powder. Dissolving in 10µg in 2.3 ml will provide a 1.0µM stock solution. Before dissolving the toxin, the tube should be centrifuged.
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
Use/Stability: Lyophilized: 2-3 weeks at room temperature, 1 year at -20°C. Reconstituted: 4 weeks at 4°C, 3 months at -20°C.
Hazard: VERY TOXIC.