货号：BML-MA1366-0025
产地：Biomol
The extracellular signal-regulated kinases (ERKs), previously known as MAP (mitogen-activated protein) kinases, are members of a family of proline-directed serine/threonine kinases that are activated by dual phosphorylation of conserved threonine and tyrosine residues within a characteristic Thr-X-Tyr peptide motif. ERK1 (p44) and ERK2 (p42) acquire full enzymatic activity upon phosphorylation of both threonine and tyrosine residues with the motif Thr-Glu-Tyr.
Product Specification
Alternative Name: MAP kinases
Formulation: Lyophilized.
Clone: AMK1
Isotype: Mouse IgG1
Immunogen: Synthetic peptide containing the motif pThr-Glu-pTyr.
Specificity: Recognizes the pThr-Glu-pTyr motif of activated mammalian ERK1/2. Does not cross-react with non-activated MAP kinases or with the phosphorylated motifs of SAPK/JNK (Thr-Pro-Tyr) or p38 kinases (Thr-Gly-Tyr).
Application: Western Blot
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
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