This peptide sequence, RRRAAEELDSRAGpSPQL, corresponds to the sequence of the ε subunit of elF2B surrounding Ser540, a target of GSK-3 (glycogen synthase kinase 3) phosphorylation, with the addition of a phosphoserine in the 4 position. This phosphoserine allows for more efficient phosphorylation of the second serine in the peptide(Km=49 µM for GSK-3ß, 83 µM for GSK-3α). Useful in phosphocellulose GSK-3α and -ß assays.
Product Specification
Alternative Name: Glycogen synthase kinase 3 substrate
MW: 1992.0
Sequence: H-Arg-Arg-Arg-Ala-Ala-Glu-Glu-Leu-Asp-Ser-Arg-Ala-Gly-pSer-Pro-Gln-Leu-OH
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
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