Sensitive fluorogenic substrate for cathepsin S and cathepsin L. Also cleaved by cathepsin B, cathepsin V, kallikrein 8, and factor VIIa/TF but not cathepsin K nor kallikrein 2. Ex.: 380 nm, Em.: 460 nm, although the following Ex/Em can also be used: 355,375/440,450. This substrate is useful for inhibitor screening and kinetic analysis. Also available: fluorogenic calibration standard AMC (BML-KI144).
Product Specification
Alternative Name: Cathepsin S & L substrate (fluorogenic)
MW: 663.8
Purity: 99%
Sequence: Z-Val-Val-Arg-AMC [Z=Cbz=Benzyloxycarbonyl; AMC=7-amino-4-methylcoumarin]
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C