产地：Biomol 
货号：BML-P214-0001
规格：1 mg
名称：R18 Peptide
保存温度：-20°C
Purity: 95%
The peptide sequence, PHCVPRDLSWLDLEANMCLP, named R18, was identified as an unphosphorylated peptide that binds to 14-3-3 proteins with high affinity (Kd=80 nM). It has been shown to bind to the same amphipathic groove on the surface of 14-3-3 as phosphorylated peptides. R18 can inhibit the formation of the 14-3-3-Raf-1 complex, reduce Raf-1 dependent transcriptional activity in cells and block the activation of ExoS by 14-3-3. It binds to all the 14-3-3 isoforms with equal affinities. This peptide is useful for competitive inhibition experiments.
A biotinylated form is available (BML-P225), allowing detection using streptavidin.
Product Specification
MW: 2309.6
Appearance: Lyophilized solid.
Sequence: Pro-His-Cys-Val-Pro-Arg-Asp-Leu-Ser-Trp-Leu-Asp-Leu-Glu-Ala-Asn-Met-Cys-Leu-Pro-OH
Solubility: Soluble in Water.
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
本产品只适合用于生命科学研究！