产地:Biomol
货号:BML-PW9860-0025
规格:25 ul
名称:p62 (human), pAb
保存温度:-20°C BML-PW9860-0100 100 µl
BML-PW9860-0025 25 µl
p62, also known as Sequestome I, is believed to serve as a scaffold protein, capable of binding to multiple signaling molecules and uniting receptor-mediated signaling events with ubiquitinylation. Elevated levels of p62 have been reported in a variety of pathologies, including within the hallmark inclusions of various neurodegenerative diseases. Immunostaining for p62 may be an important and reliable marker for the detection of neurodegenerative disease inclusion bodies. p62 serves as a molecular link between ubiquitination and autophagy by simulataneously binding both ubiquitin and LC3/GABARAP.
Product Specification
Alternative Name: SQSTM1, Sequestosome I
Formulation: Neat serum.
Immunogen: Synthetic peptide corresponding to aa 387-436 human p62.
Source/Host: From rabbit.
Specificity: Recognizes human p62.
Application: Immunohistochemistry
Western Blot
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
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