| Catalogue Number | ANT-286 |
| Type | Mouse antibody Monoclonal. |
| Introduction | HCV is a small 50nm, enveloped, single-stranded, positive sense RNA virus in the family Flaviviridae.
HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes (1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6). |
| Immunogen | Recombinant HCV peptide Mix. |
| Ig Subclass | Mouse IgG1. |
| Source | Protein-A. |
| Clone# | NYRHepC. |
| Protein Concentration | 1mg/ml in PBS (After Reconstitution). |
| Shipping Conditions | Shipped lyophilized at ambient Temperature. |
| Storage Conditions | In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
| Reconstitution | Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. |
| Stability/Shelf Life | Two years lyophilized, one month in solution at 4°C. |
| Titer | By direct ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories). |
| Applications | Direct ELISA, Western Blot, Immuneprecipitation, immunohistochemistry. |
| Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
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