Thapsigargin
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英文名：Thapsigargin CAS号：67526-95-8 产品描述Biochem/physiol ActionsPotent, cell-permeable, IP3-independent intracellular calciu
产品描述
Biochem/physiol Actions
Potent, cell-permeable, IP3-independent intracellular calcium releaser. Blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostatin. Induces apoptosis by disrupting intracellular free Ca2+ levels; incorporated into chemotherapeutic prodrug formulations.
Features and Benefits
This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.
法律信息
LOPAC is a registered trademark of Sigma-Aldrich Co. LLC
性质
| Related Categories | A to C, Adenosinetriphosphatase (microsomal calcium), Autophagy, Autophagy Inhibitors, Bioactive Small Molecule Alphabetical Index, |
| InChI Key | IXFPJGBNCFXKPI-FSIHEZPISA-N |
| Quality Level | PREMIUM |
| assay | ≥98% (HPLC) |
| form | solid film |
| solubility | acetonitrile: soluble 9.80-10.20 mg/mL |
| DMSO: soluble | |
| ethanol: soluble | |
| storage temp. | −20°C |
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