盐酸芬戈莫德
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英文名：Fingolimod Hydrochloride 存储条件：−20°C CAS号：162359-56-0 产品别名：2-氨基-2-[2-(4-辛烷基苯基)乙基]-1,3-丙二醇盐酸盐; 芬戈莫德2-amino-2-[2-(4-oct
| 货号 | 规格 | CAS号 | 包装 | 操作 |
|---|---|---|---|---|
| SML0700-5MG | ≥98% (HPLC) | 162359-56-0 | 5mg | 询底价 |
FTY720
≥98% (HPLC)
别名: 2-Amino-2-[2-(4-octyl-phenyl)-ethyl]-propane-1,3-diol hydrochloride Fingolimod hydrochloride
经验分子式（希尔表示法） C19H33NO2 · HCl
分子量 343.93
产品描述
包装
5, 25 mg in glass bottle
Biochem/physiol Actions
FTY720 is an immunomodulating drug and sphingosine 1-phosphate (S1P) receptor modulator. Phosphorylation of FTY270 by sphingosine kinase causes S1P1R internalization, which sequesters lymphocytes in lymph nodes, preventing them from taking part in an autoimmune response. Clinically, it has been approved for the treatment of multiple sclerosis (MS). It has also been shown to block and reverse paclitaxel-induced chemotherapy induced peripheral neuropathy (CIPN) through S1PR inhibition as well as inhibit the activity of histone deacetylases in the hippocampus of mouse brains, thereby modulating memory.
性质
| Related Categories | Bioactive Small Molecule Alphabetical Index, F,Immune Cell Signaling and Blood, Immune System Regulation, Immunomodulators and Antibiotics, |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | white to beige |
| solubility | water: 10 mg/mL, clear |
| storage temp. | −20°C |
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