| 应用 |
Dacarbazine is a triazine antineoplastic agent that is used for DNA methylation via formation of methyl adducts. It is used to treat metastatic malignant melanomas and Hodgkin′s when used in combination with other antineoplastic agents. |
| 产品介绍 |
Dacarbazine是一种抗肿瘤化疗药物，用于治疗多种癌症。 |
| 备注 |
Dacarbazine is an antineoplastic chemotherapy drug used in the treatment of various cancers. |
| 生化机理 |
Dacarbazine appears to exert cytotoxic effects by acting as an alkylating agent, by inhibiting DNA synthesis as a purine analog, and by inducing apoptosis and hepatotoxicity in mice. Dacarbazine is not cell cycle-phase specific. |
| 别名 |
DTIC;达卡巴嗪;5-(3,3-二甲基-1-三氮烯)咪唑-4-羧酰胺; 氮烯咪胺;DTIC;5-(3,3-Dimethyltriazeno)imidazole-4-carboxamide;DTIC-Dome; Imidazole Carboxamide; 4-(3,3-Dimethyltriazeno)imidazole-5-carboxamide; 4-(Dimethyltriazeno)imidazole-5-carboxamide |
