Rucaparib (AG-014699,PF-01367338)-分析测试百科网

Rucaparib (AG-014699,PF-01367338)

面议

分子式 C19H18FN3O·H3PO4 分子量421.36 属性溶解性 DMSO 84 mg/mL Water <1 mg/mL Ethanol <1 mg/mL 存贮条件储存温度-20°C //decorateTable

400-6699-117 转1000

耗材描述

溶解性	DMSO 84 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
存贮条件	储存温度-20°C

产品介绍	Rucaparib (AG-014699,PF-01367338)是一种PARP抑制剂，作用于PARP1的Ki为1.4 nM，对其余8个PARP位点也有结合亲和力。Phase 3。
备注	Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with K_i of 1.4 nM for PARP1, also showing binding affinity to eight other PARP domains. Phase 1/2.
别名	8-氟-1,3,4,5-四氢-2-[4-[(甲基氨基)甲基]苯基]-6H-吡咯并[4,3,2-ef][2]苯并氮杂卓-6-酮磷酸盐;AG014699 phosphate; PF01367338 phosphate;8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one phosphate