BIX 02188-分析测试百科网

BIX 02188

面议

分子式 C25H24N4O2 分子量412.48 属性溶解性 DMSO 43 mg/mL Water <1 mg/mL Ethanol 3 mg/mL 存贮条件储存温度-20°C //decorateTable('product-

400-6699-117 转1000

耗材描述

溶解性	DMSO 43 mg/mL Water <1 mg/mL Ethanol 3 mg/mL
存贮条件	储存温度-20°C

产品介绍	BIX 02188是一种选择性的MEK5抑制剂，IC50为4.3 nM，也抑制ERK5催化活性，IC50为810 nM，且不抑制与其密切相关的激酶MEK1， MEK2， ERK2，和JNK2
备注	BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM, also inhibits ERK5 catalytic activity with IC50 of 810 nM, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.
别名	3-[[[3-[(二甲基氨基)甲基]苯基]氨基]苯基亚甲基]-2,3-二氢-2-氧代-1H-吲哚-6-甲酰胺;3-[[[3-[(Dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-1H-indole-6-carboxamide