PLX-4720-分析测试百科网

PLX-4720

面议

分子式 C17H14ClF2N3O3S 分子量413.83 属性溶解性 DMSO 83 mg/mL Water <1 mg/mL Ethanol <1 mg/mL 存贮条件储存温度-20°C //decorateTable(

400-6699-117 转1000

耗材描述

溶解性	DMSO 83 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
存贮条件	储存温度-20°C

备注	PLX4720 is a potent and selective inhibitor of B-Raf^V600E with IC50 of 13 nM, equally potent to c-Raf-1(Y340D and Y341D mutations), 10-fold selectivity for B-RafV600E than wild-type B-Raf.
生化机理	PLX-4720 is a B-raf inhibitor with IC50 of 160 nM.
别名	N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide;N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide