耗材描述

• 分子式 C₃₈H₆₉NO₁₃
• 分子量747.95
• Beilstein号
• EC号
• MDL号 MFCD00865140
• PubChem编号

属性

熔点	225°C
旋光率	-92°C
溶解性	Soluble in ethanol (<1 mg/ml), water (<1 mg/ml), acetone (50 mg/ml), DMSO (18 mg/ml), and methanol.
存贮条件	储存温度 2-8°C

描述

应用	A macrolide antibiotic and protein synthesis inhibitor
产品介绍	Clarithromycin 是一种大环内酯类抗生素，是CYP3A4抑制剂。
备注	Clarithromycin (Biaxin, Klacid) is a macrolide antibiotic and a CYP3A4 inhibitor.
生化机理	Clarithromycin is a 14-member ring macrolide antibiotic and 6-O-methyl derivative of erythromycin. Clarithromycin has reported bacteriostatic action against gram-positive bacteria and some gram-negative bacteria including anaerobes. Similar to other macrolide antibiotics, this antibiotic is believed to function via binding of the ribosome within the microorganism. Studies have noted that Clarithromycin appears to bind specifically to the 50S ribosomal subunit, thus inhibiting DNA translation and inhibiting bacterial growth. This compound is both a substrate and inhibitor of CYP3A4.
别名	克拉仙;克拉霉素;甲氧基红霉素;Biaxin; Biaxin XL; Clarosip; Klaricid; Cyllind;6-O-Methylerythromycin; A-56268; TE-03

标识符号	GHS07
信号词	Warning
危害声明	H302
个人防护设备	dust mask type N95 (US), Eyeshields, Gloves
RTECS	KF4997000
WGK德国	3

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