Tolcapone
面议
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分子式 C14H11NO5 分子量273.24 MDL号 MFCD00866569 属性 溶解性 Soluble in water (partly), DMSO (55 mg/ml at 25 °C), and water (5
| 货号 | CAS号 | 操作 |
|---|---|---|
| T125285-250mg | 134308-13-7 | 询底价 |
| T125285-50mg | 134308-13-7 | 询底价 |
| T125285-10mg | 134308-13-7 | 询底价 |
耗材描述
-
分子式 C14H11NO5
- 分子量273.24
- MDL号 MFCD00866569
属性
| 溶解性 | Soluble in water (partly), DMSO (55 mg/ml at 25 °C), and water (55 mg/ml at 25 °C). |
| 存贮条件 | 储存温度 2-8°C |
描述
| 应用 | An inhibitor of peripheral and central catechol-O-methyltransferase. |
| 产品介绍 | Tolcapone是一种有效和选择性的可逆硝基酚类儿茶酚-O-甲基转移酶(COMT)抑制剂，Ki为30nM。 |
| 备注 | Tolcapone is a selective, potent and reversible of catechol-O-methyl transferase (COMT) inhibitor with Ki of 30 nM. |
| 生化机理 | Tolcapone is a orally active inhibitor of peripheral and COMT (central catechol-O-methyltransferase). Antiparkinsonian. |
| 别名 | 托卡朋; (3,4-二羟基-5-硝基苯基)-(4-甲基苯基)甲酮;Ro 40-7592; Tasmar;(3,4-Dihydroxy-5-nitrophenyl)-(4-methylphenyl)methanone |
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