耗材描述

• 分子式 C₂₃H₂₂ClNO₂
• 分子量379.88

属性

熔点	165-167 °C
溶解性	Soluble in water (0.5 mg/ml at 25 °C), ethanol (~5 mg/ml), DMSO (20 mg/ml), DMF (20 mg/ml), and methanol.
存贮条件	储存温度-20°C

描述

应用	An inhibitor of Cox-1, Cox-2, and 5-lipoxygenase.
产品介绍	Licofelone是COX/LOX的双重抑制剂，用于治疗骨关节炎。
备注	Licofelone is a dual COX/LOX inhibitor being considered as a treatment for osteoarthritis.
生化机理	Licofelone is an anti-inflammatory and dual inhibitor of cyclooxygenase and 5-LO(5-lipoxygenase). Licofelone inhibits both Cox-1 and Cox-2.
别名	利克飞龙; 2-[2-(4-氯苯基)-6,6-二甲基-1-苯基-5,7-二氢吡咯烷嗪-3-基]乙酸;ML-3000;ML-3000;2-[2-(4-Chlorophenyl)-6,6-dimethyl-1-phenyl-5,7-dihydropyrrolizin-3-yl]acetic acid; [2,2-Dimethyl-6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl]acetic acid

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