Lidocaine
面议
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分子式 C14H22N2O 分子量234.34 Beilstein号 12(4)2538 EC号 205-302-8 MDL号 MFCD00026733 PubChem编号 24896480 属性 敏感性 对空气、光线敏感 溶解性 Solu
| 货号 | CAS号 | 操作 |
|---|---|---|
| L129221-100g | 137-58-6 | 询底价 |
| L129221-25g | 137-58-6 | 询底价 |
| L129221-5g | 137-58-6 | 询底价 |
耗材描述
- 分子式 C14H22N2O
- 分子量234.34
- Beilstein号 12(4)2538
- EC号 205-302-8
- MDL号 MFCD00026733
- PubChem编号 24896480
属性
| 敏感性 | 对空气、光线敏感 |
| 溶解性 | Soluble in ethanol (50 mg/ml), water (9 mg/ml at 25 °C), methanol, DMSO (47 mg/ml at 25 °C), and chloroform. |
| 存贮条件 | 充氩保存;储存温度2-8°C |
描述
| 应用 |
A selective inverse peripheral histamine H1-receptor agonist 利多卡因可作为内参，使用气相色谱（GLC）测定人血清样品中的哌可昔林。 |
| 产品介绍 | Lidocaine是一种选择性的，逆向外周组胺H1受体激动剂，IC50大于32 μM。 |
| 备注 | Lidocaine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. |
| 生化机理 | Lidocaine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Lidocaine is also an anasthetic and class Ib antiarrhythmic agent. This compund is known to block voltage-gated sodium channels in the inactivated state. Lidocaine is a second-generation antihistamine agent closely structurally related to tricyclic antidepressants such as imipramine, and distantly related to the atypical antipsychotic quetiapine, used to treat allergies. Na+通道阻滞剂；在肠胃外给药后可迅速被吸收的IB类抗心律失常药。 |
| 别名 | 利多卡因;昔罗卡因;赛罗卡因;利多卡因碱;N-二乙氨基乙酰基-2,6-二甲基苯胺;2-二乙基氨基-N-(2,6-二甲基苯基)乙酰胺；赛洛卡因;2-Diethylamino-N-(2,6-dimethylphenyl)acetamide;Lignocaine;Xylocaine |
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