Fluoxetine HCl
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分子式 C17H18F3NO·HCl 分子量345.79 Beilstein号 EC号 260-101-2 MDL号 MFCD00214288 PubChem编号 24278096 属性 溶解性 Soluble in water (4 mg
货号 | CAS号 | 操作 |
---|---|---|
F131623-1g | 56296-78-7 | 询底价 |
F131623-25g | 56296-78-7 | 询底价 |
F131623-5g | 56296-78-7 | 询底价 |
耗材描述
- 分子式 C17H18F3NO·HCl
- 分子量345.79
- Beilstein号
- EC号 260-101-2
- MDL号 MFCD00214288
- PubChem编号 24278096
属性
溶解性 | Soluble in water (4 mg/mL), DMSO (>5 mg/mL), acetone, acetonitrile, chloroform, and methanol. |
存贮条件 | 储存温度2-8℃ |
描述
应用 | An ST (SERT) inhibitor. |
产品介绍 | Fluoxetine HCl是一种抗抑郁剂,选择性抑制5-羟色胺再摄取。 |
备注 | Sold under license from Eli Lilly and Company.Store, as supplied, at room temperature for up to 1 year. Store solutions at -20°C for up to 3 months. |
生化机理 | Fluoxetine is an ST (5-hydroxytryptamine/serotonin/5-HT reuptake) inhibitor. This is a racemic mixture and both R and S enantiomers which are reported to inhibit 5-HT uptake in synaptosomal preparations of rat cerebral cortex. Additionally, Fluoxetine is also noted to increase extracellular levels of 5-HT in several areas of the rat brain as a result of reuptake inhibition. This increase in availability of 5-HT is reported to lead to a decrease in synthesis and turnover of 5-HT. |
别名 | 氟西汀 盐酸盐;(±)-N-甲基-γ-[4-(三氟甲基)苯氧基]苯基丙胺 盐酸盐;LY-110,140 盐酸盐;盐酸氟西汀;(±)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride;LY-110,140 hydrochloride;N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine Hydrochloride;LY110140; LY 110140; LY-110140 |
Reaxys-RN | 6759273 |
标识符号 | GHS05, GHS07, GHS09 |
信号词 | Danger |
危害声明 | H302,H318,H400 |
警示性声明 | P273,P280,P305+P351+P338 |
个人防护设备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
RTECS | UI4050000 |
WGK德国 | 3 |
风险声明 (欧洲) | R22;R41;R50 |
安全声明(欧洲) | S26;S39;S61 |
危害码(欧洲) | Xn,N |
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