Celecoxib
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分子式 C17H14F3N3O2S 分子量381.37 Beilstein号 EC号 MFCD00941298 MDL号 MFCD00941298 PubChem编号 属性 敏感性 对热、光线敏感 溶解性 , Soluble in DMSO
| 货号 | CAS号 | 操作 |
|---|---|---|
| C129279-100g | 169590-42-5 | 询底价 |
| C129279-100mg | 169590-42-5 | 询底价 |
| C129279-25g | 169590-42-5 | 询底价 |
| C129279-5g | 169590-42-5 | 询底价 |
耗材描述
- 分子式 C17H14F3N3O2S
- 分子量381.37
- Beilstein号
- EC号 MFCD00941298
- MDL号 MFCD00941298
- PubChem编号
属性
| 敏感性 | 对热、光线敏感 |
| 溶解性 | , Soluble in DMSO (76 mg/ml at 25 °C), methanol, ethanol (33 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and dichloromethane., Soluble in DMSO (76 mg/ml at 25 °C), methanol, ethanol (33 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and dichloromethane |
| 存贮条件 | 储存温度-20°C |
描述
| 应用 | A selective Cox-2 inhibitor |
| 产品介绍 | Celecoxib是环氧合酶-2(COX-2)选择性抑制剂，IC50为40 nM。 |
| 备注 | Celecoxib is a selective COX-2 inhibitor with IC50 of 40 nM. |
| 生化机理 | Celecoxib is a selective cyclooxygenase-2 (Cox-2) inhibitor (IC50 = 40 nM) with low sensitivity against Cox-1. Celecoxib shows an anti-proliferative effect on nasopharyngeal carcinoma (NPC) cell lines including HNE1 (IC50 = 32.86 μM) and CNE1-LMP1 (IC50 = 61.31 μM). |
| 别名 | 塞内昔布; 赛利克西; 4-[5-(4-甲基苯基)-3-(三氟甲基)吡挫-1-基]苯磺酰胺;4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; CJ-016377; CP-598107; PF-00345549; Celebrex; Celebra PHA-00846533 SC-58635 YM-177 |
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