Nefiracetam
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分子式 C14H18N2O2 分子量246.30 Beilstein号 EC号 MDL号 MFCD00209882 PubChem编号 属性 溶解性 Soluble in DMSO (49 mg/ml at 25 °C), water (5
| 货号 | CAS号 | 操作 |
|---|---|---|
| N129604-1g | 77191-36-7 | 询底价 |
| N129604-250mg | 77191-36-7 | 询底价 |
| N129604-50mg | 77191-36-7 | 询底价 |
耗材描述
- 分子式 C14H18N2O2
- 分子量246.30
- Beilstein号
- EC号
- MDL号 MFCD00209882
- PubChem编号
属性
| 溶解性 | Soluble in DMSO (49 mg/ml at 25 °C), water (5 mg/ml at 25 °C), and ethanol (49 mg/ml at 25 °C). |
描述
| 应用 | Activator of L/N-type calcium channels, cholinergic, monoaminergic and GABAergic systems. |
| 产品介绍 | Nefiracetam作用于Ro 5-4864引起的抽搐，是GABAergic，胆碱及单胺类的神经系统增强剂。 |
| 备注 | Nefiracetam is a GABAergic, cholinergic, and monoaminergic neuronal systems enhancer for Ro 5-4864-induced convulsions. Phase 2. |
| 生化机理 | Nefiracetam is a nootropic of the racetam family. Nefiracetam is cognitive enhancer with an IC50 of approximately 150–200 μM for Ro 5-4864. This compound activates L/N-type calcium channels, cholinergic, monoaminergic and GABAergic systems. Nefiracetam displays potent neuroprotective action in the retinal ischemia-reperfusion model. |
| 别名 | 奈非西坦; N-(2,6-二甲基苯基)-2-氧代-1-吡咯烷乙酰胺;(2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)-acetamide); DM-9384;N-(2,6-dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide; Translon |
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