Dipyridamole
面议
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分子式 C24H40N8O4 分子量504.63 Beilstein号 26(3/4)3840 EC号 200-374-7 MDL号 MFCD00010555 PubChem编号 24277705 属性 熔点 165-166 °C 溶解性
| 货号 | CAS号 | 操作 |
|---|---|---|
| D129205-1g | 58-32-2 | 询底价 |
| D129205-25g | 58-32-2 | 询底价 |
| D129205-5g | 58-32-2 | 询底价 |
耗材描述
- 分子式 C24H40N8O4
- 分子量504.63
- Beilstein号 26(3/4)3840
- EC号 200-374-7
- MDL号 MFCD00010555
- PubChem编号 24277705
属性
| 熔点 | 165-166 °C |
| 溶解性 | Soluble in chloroform, methanol, dilute acids, ethanol (10 mM), DMSO (100 mM), and water (slightly soluble). |
描述
| 应用 | A phosphodiester, cGMP, and non-specific nucleoside transport inhibitor. |
| 产品介绍 | Dipyridamole是一种磷酸二酯酶抑制剂，通过红细胞和血管内皮细胞，抑制腺苷的摄取和代谢。 |
| 备注 | Dipyridamole (Persantine) is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. |
| 生化机理 | Dipyridamole is a PDE (phosphodiesterase) inhibitor with antioxidant properties. This compound has been shown to suppress high glucose-induced osteopontin mRNA expression and protein secretion, as well as inhibit cAMP and cGMP hydrolysis. Research indicates that Dipyridamole is a non-specific nucleoside transport inhibitor with the ability to increase the effects of adenosine in sinoatrial and atrioventricular nodes. Dipyridamole is an inhibitor of ENT1 and ENT2 |
| 别名 | 双嘧达莫;潘生丁; 双嘧哌胺醇; 2,6-双(二羟乙基氨基)-4,8-二哌啶基嘧啶并[5,4-d]嘧啶;2,6-Bis(diethanolamine)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine;2,2',2'',2'''-[(4,8-Dipiperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakisethanol;Persantin; Curanty |
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