生化机理 |
Darapladib, is a novel inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2), an enzyme that may link lipid metabolism with inflammation, leading to the increased stability of atherosclerotic plaques present in the major arteries. Darapladib is being studied as a possible add-on treatment for atherosclerosis. |
别名 |
SB-480848;SB480848;SB 480848;N-[2-(二乙氨基)乙基]-N-[4'-(三氟甲基)-1,1'-联苯-4-甲基]-2-[2-(4-氟苄硫基)-4-氧代-4,5,6,7-四氢-1H-环戊并[d]嘧啶-1-基]乙酰胺;SB-480848;SB480848;SB 480848;N-[2-(Diethylamino)ethyl]-N-[4'-(trifluoromethyl)-1,1'-biphenyl-4-ylmethyl]-2-[2-(4-fluorobenzylthio)-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl]acetamide |