耗材描述

• 分子式 C₂₅H₂₄F₂N₂O₃
• 分子量438.48
• EC号 MFCD13181507

属性

溶解性	DMSO 33 mg/mL Water <1 mg/mL Ethanol 2 mg/mL
存贮条件	储存温度-20°C

描述

备注	XL335 is a potent, selective FXR agonist with EC50 of 4 nM, highly selective versus other nuclear receptors, such as LXR, PPAR, ER and etc. Phase 1.
生化机理	WAY-362450 (XL335; WAY 362450; Turofexorate isopropyl) is a highly potent, selective, and orally active farnesoid X receptor (FXR) agonist with an EC50 of 4 nM.WAY-362450 (XL335; WAY 362450; Turofexorate isopropyl) is useful for dyslipidemia
别名	(E)-isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate;(E)-isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate

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