耗材描述

• 分子式 C₁₈H₁₈F₃N₃O
• 分子量349.35

属性

溶解性	Soluble in DMSO (70 mg/mL at 25 °C), ethanol (70 mg/mL at 25 °C), and water (<1 mg/mL at 25 °C).
存贮条件	储存温度2-8°C

描述

应用	An SRPK1 inhibitor.
产品介绍	SRPIN340是选择性SRPK抑制剂，作用于SRPK1, Ki为0.89 μM ，对其他140多种激酶没有显著的抑制活性。
备注	SRPIN340 is a selective SRPK inhibitor with Ki of 0.89 μM for SRPK1, showing no significant inhibitory activity against other >140 kinases..
生化机理	SRPIN 340 is a selective inhibitor of serine–arginine protein kinase 1 (SRPK1), a protein kinase that phosphorylates proteins containing serine-arginine-rich domains. SRPIN 340 is competitive with ATP and does not inhibit other SRPKs significantly.
别名	N-[2-(1-哌啶基)-5-(三氟甲基)苯基]-4-吡啶甲酰胺;SRPIN 340;SRPIN-340;SRPK inhibitor;N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide

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