| 应用 |
An antibiotic related to penicillin |
| 产品介绍 |
Piperacillin is a semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. |
| 备注 |
Piperacillin is a semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. |
| 生化机理 |
Piperacillin is anantibiotic. It is an extended-spectrum beta-lactam of the ureidopenicillin class.The chemical structure of Piperacillin and other ureidopenicillins incorporates a polar side chain that enhances penetration into Gram-(-) bacteria and reduces susceptibility to cleavage by Gram-(-) beta lactamase enzymes. These properties confer activity against the important hospital pathogen Pseudomonas aeruginosa. Thus Piperacillin is sometimes referred to as an anti-pseudomonal penicillin.When used alone, Piperacillin lacks strong activity against the Gram-(+) pathogenStaphylococcus aureus, as it Piperacillin is broken down by the Gram-(+) beta lactamases. |
| 别名 |
哌拉西林钠; (2S,5R,6R)-3,3-二甲基-6-((4-乙基-2,3-二氧代-1-哌嗪甲酰氨基)苯乙酰氨基)-7-氧代-4-硫杂-1-氮杂双环(3.2.0)庚烷-2-甲酸钠盐;Pipracil;Sodium piperacillin; Piperacillin Sodium Salt;(2s-(2alpha,5alpha,6beta(s*)))-6-(((((4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl)amino)phenylacetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid monosodium salt |
