PRX-08066-分析测试百科网

PRX-08066

面议

分子式 C19H17ClFN5S 分子量401.89 属性溶解性 DMSO 存贮条件储存温度-20°C //decorateTable('product-attribute-specs-table') 描述生化机理 PRX-08066

400-6699-117 转1000

货号	CAS号	操作
P127869-5mg	866206-54-4	询底价

耗材描述

溶解性	DMSO
存贮条件	储存温度-20°C

生化机理	PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR) antagonist that causes selective vasodilation of pulmonary arteries. PRX-08066 significantly reduced peak PA pressure at 50 and 100 mg/kg (P < 0.05 and < 0.01, respectively) compared with MCT control animals. The 5-HT2BR antagonist PRX-08066 significantly attenuated the elevation in PA pressure and RV hypertrophy and maintained cardiac function. PRX-08066 prevents the severity of PAH in the MCT rat model.