耗材描述

• 分子式 C₁₁H₁₇NO·HCl
• 分子量215.72

属性

熔点	200-205 °C
溶解性	Soluble in methanol (50 mg/ml), water (100 mM), DMSO (100 mM), chloroform, and alcohol.
存贮条件	储存温度 2-8°C

描述

应用	A use dependent blocker of sodium channels.
产品介绍	Mexiletine HCl 属于IB类抗心律失常药，抑制钠离子通道，降低内流钠电流。
备注	Mexiletine HCl belongs to Class IB anti-arrhythmic group of medicines, inhibits sodium channels to reduce the inward sodium current.
生化机理	Mexiletine hydrochloride is a use dependent blocker of sodium channels in skeletal muscle tissue. In addition, mexiletine can plays an important role in protecting neuronal tissue from oxidative damage. The aryloxy moiety of mexiletine is very important to its function as a sodium channel blocker, as any change to this structure reduces the potency of the compound.
别名	1-(2,6-二甲基苯氧基)-2-丙胺盐酸盐;盐酸美西律;1-(2,6-Dimethylphenoxy)-2-propylamine Hydrochloride;1-(2,6-Xylyloxy)-2-aminopropane hydrochloride;Mexiletine hydrochloride

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