BAY 80-6946 (Copanlisib)-分析测试百科网

BAY 80-6946 (Copanlisib)

面议

品牌：阿拉丁
厂商性质：生产商
产地类别：国产
产地：上海
货期：现货
服务地域：全国
规格：5
近期咨询：0

分子式 C23H28N8O4 分子量480.52 Beilstein号 EC号 MDL号 PubChem编号属性溶解性 DMSO 0.002 mg/mL Water 0.002 mg/mL Ethanol 0.01 mg/mL 存贮条件

上海阿拉丁生化科技股份有限公司

上海阿拉丁生化科技股份有限公司

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货号	CAS号	操作
B129540-10mg	1032568-63-0	询底价
B129540-1mg	1032568-63-0	询底价
B129540-250mg	1032568-63-0	询底价
B129540-50mg	1032568-63-0	询底价
B129540-5mg	1032568-63-0	询底价

耗材描述

分子式 C₂₃H₂₈N₈O₄
分子量480.52
Beilstein号
EC号
MDL号
PubChem编号

属性

溶解性	DMSO 0.002 mg/mL Water 0.002 mg/mL Ethanol 0.01 mg/mL
存贮条件	储存温度2-8℃

描述

备注	BAY 80-6946 is a potent and highly selective reversible PI3K inhibitor for PI3Kα/β with IC50 of 0.469 nM/3.72 nM. Phase 1.
生化机理	BAY 80-6946 is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BAY 80-6946 inhibits the activation of the PI3K signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents.
别名	5-Pyrimidinecarboxamide, 2-amino-N-[2,3-dihydro-7-methoxy-8-[3-(4-morpholinyl)propoxy]imidazo[1,2-c]quinazolin-5-yl]-;5-Pyrimidinecarboxamide, 2-amino-N-[2,3-dihydro-7-methoxy-8-[3-(4-morpholinyl)propoxy]imidazo[1,2-c]quinazolin-5-yl]-

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