Saxagliptin-分析测试百科网

Saxagliptin

面议

分子式 C18H25N3O2 分子量315.41 Beilstein号 EC号 MDL号 PubChem编号属性溶解性 DMSO 63 mg/mL Water 63 mg/mL Ethanol 24 mg/mL 存贮条件储存温度-20

400-6699-117 转1000

耗材描述

溶解性	DMSO 63 mg/mL Water 63 mg/mL Ethanol 24 mg/mL
存贮条件	储存温度-20°C

产品介绍	Saxagliptin(BMS477118)是选择性可逆的DPP4抑制剂，IC50和Ki分别为26 nM和1.3 nM。
备注	Saxagliptin is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.
生化机理	Saxagliptin is a drug which was developed for the treatment of respiratory disorders such as asthma and Chronic Obstructive Pulmonary Disease (COPD). It is orally active and acts as a selective Phosphodiesterase-4 inhibitor.
别名	沙克列汀；沙格列汀；(1S,3S,5S)-2-[(2S)-2-氨基-2-(3-羟基三环[3.3.1.1(3,7)]癸烷-1-基)乙酰基]-2-氮杂双环[3.1.0]己烷-3-腈；;BMS-477118；Onglyza；BMS 477118；BMS477118；