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分子式 C45H74O11 分子量791.07(for Oligomycin A) Beilstein号 7615308 EC号 MDL号 MFCD00065705 PubChem编号 24898006 属性 熔点 84-100°C 溶解性
| 货号 | CAS号 | 操作 |
|---|---|---|
| O111756-5mg | 1404-19-9 | 询底价 |
| O111756-25mg | 1404-19-9 | 询底价 |
耗材描述
- 分子式 C45H74O11
- 分子量791.07(for Oligomycin A)
- Beilstein号 7615308
- EC号
- MDL号 MFCD00065705
- PubChem编号 24898006
属性
| 熔点 | 84-100°C |
| 溶解性 | Soluble in EtOH, acetone (50 mg/ml), DMSO (300 mg/ml), ethanol, and methanol. Insoluble in water |
| 存贮条件 | 储存温度 2-8°C |
描述
| 应用 | A specific inhibitor of the mitochondrial ATP-synthase. |
| 产品介绍 | Oligomycin is a macrolide that acts as a specific inhibitor of the mitochondrial ATP-synthase and blocks oxidative phosphorylation. The compound is a mixture of isomers A ,B , and C .Cancer cell studies show that Oligomycin does not activate the hypoxia-induced factor, however, it enhances the bioenergetic adaptation of heterogeneous bioenergetically organized cells. Oligomycin has been shown to decreased the cyclin D1 protein expression levels |
| 备注 | 该产品为A, B 和 C的混合物 |
| 生化机理 | Macrolide antibiotic; inhibits mitochondrial ATPase and phosphoryl group transfer. |
| 别名 | Oligomycin;Oligomycin a, b, c mixture |
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