磷脂酶A2 来源于东部菱背响尾蛇毒液
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分子式 分子量 Beilstein号 EC号 232-637-7 MDL号 MFCD00131890 PubChem编号 属性 存贮条件 储存温度 2-8°C //decorateTable('product-attribute-specs
货号 | CAS号 | 操作 |
---|---|---|
P128568-1mg | 9001-84-7 | 询底价 |
耗材描述
- 分子式
- 分子量
- Beilstein号
- EC号 232-637-7
- MDL号 MFCD00131890
- PubChem编号
属性
存贮条件 | 储存温度 2-8°C |
描述
应用 | Phospholipase A2 has been used in phospholipase assay and to determine rat renal proximal tubular segments (PTS) viability during oxygenation and hypoxia-reoxygenation. |
产品介绍 | Phospholipase A2 is a member of the class of heat-stable, calcium-dependent enzymes catalyzing the hydrolysis of the 2-acyl bond of 3-n-phosphoglycerides. The enzyme has a molecular weight of 30,000 daltons. Phospholipase A2 is activated by Ca2+. It is inhibited by zinc, barium, and manganese ions. Activity values for phospholipase A preparations which are derived from titrimetric assay procedures can be quite dependent on source and type of lecithin, its preparation as a substrate emulsion, other components of the reaction mixture, and the method and instrumentation used. |
备注 | A chromatographically purified, dialyzed, lyophilized powder. |
生化机理 | Hydrolyzes the β-ester bond of zwitterionic glycerophospholipids. Preferred substrates are phosphatidylcholine, phosphatidylethanolamine, and their plasmalogen analogues. Phosphatidylinositol and phosphatidylserine are also hydrolyzed. Aggressively attacks phospholipids in membranes of intact cells. It has a high catalytic activity on aggregated substrates compared to monomeric substrates. |
别名 | ;PLA2;Lecithinase A;Phosphatidylcholine 2-acylhydrolase |
个人防护设备 | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
RTECS | SZ6114900 |
WGK德国 | 3 |
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