1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-5000] (ammonium salt)-分析测试百科网

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate(polyethylene glycol)-5000] (ammonium salt)

面议

品牌：阿拉丁
厂商性质：生产商
产地类别：国产
产地：上海
货期：现货
服务地域：全国
规格：4
近期咨询：0

分子式 C287H558N11O127P 分子量6226.473 属性存贮条件储存温度：-20°C //decorateTable('product-attribute-specs-table') 描述产品介绍 Folate rece

上海阿拉丁生化科技股份有限公司

上海阿拉丁生化科技股份有限公司

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货号	CAS号	操作
D130797-10mg	1236288-25-7	询底价
D130797-5mg	1236288-25-7	询底价
D130797-1mg	1236288-25-7	询底价
D130797-500ug	1236288-25-7	询底价

耗材描述

分子式 C₂₈₇H₅₅₈N₁₁O₁₂₇P
分子量6226.473

属性

存贮条件	储存温度：-20°C

描述

产品介绍	Folate receptors are cellular surface markers for numerous solid tumors and myeloid leukemias. Avanti now offers a derivative, DSPE-PEG-folate, which can be incorporated into liposomes as a targeting ligand. Folate targeted drug delivery has emerged as an alternative therapy for the treatment and imaging of many cancers and inflammatory diseases. Due to its small molecular size and high binding affinity for cell surface folate receptors (FR), folate conjugates have the ability to deliver a variety of molecular complexes to pathologic cells without causing harm to normal tissues. Complexes that have been successfully delivered to FR expressing cells, to date, include protein toxins, immune stimulants, chemotherapeutic agents, liposomes, nanoparticles, and imaging agents. This review will summarize the applications of folic acid as a targeting ligand and highlight the various methods being developed for delivery of therapeutic and imaging agents to FR-expressing cells.
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