耗材描述

• 分子式 C₂₇H₄₄O₂
• 分子量400.64
• Beilstein号
• EC号 255-297-1
• MDL号 MFCD00868328
• PubChem编号 24850815

属性

存贮条件

储存温度-20°C

描述

备注	本产品只用于科研之用。
生化机理	Synthetic vitamin D3 analog that is metabolized to 1,25-dihydroxycholecalcif?erol. Inhibits bone resorption and stimulates bone formation. Supresses parathyroid hormone secretion by bovine parathyroid cells. Cholecalciferol is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs. 1α-Hydroxyvitamin D3 (alfacalcidol is a synthetic analog that is metabolized to 1,25-dihydroxycholecalcif?erol, the biologically active form of vitamin D3 in calcium absorption and deposition. 1α,25-Dihydroxyvitamin D3 has widespread effects on cellular differentiation and proliferation, and can modulate immune responsiveness, and central nervous system function. Recent studies suggest that 1α,25-dihydroxyvitamin D3 acts as a chemopreventive agent against several malignancies including cancers of the prostate and colon and shows synergy with other anticancer compounds.
别名	;1α-Hydroxycholecalciferol, Alfacalcidol 1α-Hydroxyvitamin D3

标识符号	GHS06
信号词	Danger
危害声明	H300,H310,H330
警示性声明	P260,P264,P280,P284,P302+P350,P310
个人防护设备	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECS	VS2851000
WGK德国	3
风险声明 (欧洲)	R26/27/28
安全声明（欧洲）	S28;S36/37;S45
危害码（欧洲）	T+

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