耗材描述

• 分子式 C₆₄H₉₁CoN₁₃O₁₆P
• 分子量1388.41
• Beilstein号
• EC号 245-019-7
• MDL号 MFCD00082532
• PubChem编号

属性

熔点	>3000°C
敏感性	空气及热敏感
溶解性	Soluble in Water
存贮条件	储存温度 2-8℃,充氩保存

描述

应用	A physiological analog of vitamin B12
产品介绍	Hydroxocobalamin Acetate is a physiological analog of vitamin B12 existing in an aqueous solution as an equilibrium mixture of its hydroxy isomer and the ionic aqua isomer where the CN group is replaced with OH. It is a precursor of the methylcobalamin and cobamam coenzymes.
生化机理	Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. The physiologically active forms of vitamin B12 include methylcobalamin and adenosylcobalamin, whereas hydroxocobalamin (vitamin B12a, OHCbl) and cyanocobalamin (CNCbl) are storage and delivery forms. Bacteria-derived hydroxocobalamin (OHCbl) and CNCbl are converted in humans to useful coenzyme forms to support metabolic processes such as mitochondrial methylmalonylcoenzyme A mutase conversion of methylmalonic acid (MMA) to succinate to link lipid and carbohydrate metabolism, and activation of methionine synthase, the rate limiting step in the synthesis of methionine.
别名	醋酸羟钴胺；维生素 B12a 醋酸盐;Vitamin B12a Acetate

Reaxys-RN	19236547
标识符号	GHS08
信号词	Warning
危害声明	H351
警示性声明	P281
RTECS	GG3740000
WGK德国	3

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