耗材描述

• 分子式 C₁₉H₂₁NS
• 分子量295.44
• Beilstein号
• EC号
• MDL号 MFCD00864192
• PubChem编号

属性

溶解性	DMSO : 20 mg/mL (67.70 mM; Need ultrasonic) H2O : < 0.1 mg/mL (insoluble)
存贮条件	储存温度-20°C

描述

应用	Pizotifen (BC-105) is a potent 5-HT2 receptor antagonist, with a high affinity for 5-HT1C binding site. Pizotifen is an antidepresent 5-HT2A receptor antagonist and has the capacity to inhibit serotonin-enhanced ADP-induced platelet aggregation.
产品介绍	Pizotifen (BC-105) 是 5-HT2 受体的有效拮抗剂，并对 5-HT1C 有高亲和力。
生化机理	Pizotifen is a serotonin antagonist acting mainly at the 5-HT1, 5-HT2A and 5HT2C receptors with some antihistamine activity. It is used for the prevention of vascular headache including migraine and cluster headache.
别名	苯噻啶; 新度美安; 4-[9,10-二氢-4H-苯并[4,5]环庚烷并[1,2-b]噻吩-4-亚基]-1-甲基哌啶 ;BC-105;Pizotyline;Sandomigran; 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine

Reaxys-RN	753534
信号词	Warning
危害声明	H302-H361
警示性声明	P281
RTECS	TM7165000
WGK德国	3

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