皮质甾酮
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分子式 C21H30O4 分子量346.46 Beilstein号 2339601 EC号 200-019-6 MDL号 MFCD00037715 PubChem编号 24856812 属性 熔点 179-183°C 溶解性 Soluble
货号 | CAS号 | 价格 | 操作 |
---|---|---|---|
C119329-100mg | 50-22-6 | ¥699.00 | 询底价 |
耗材描述
- 分子式 C21H30O4
- 分子量346.46
- Beilstein号 2339601
- EC号 200-019-6
- MDL号 MFCD00037715
- PubChem编号 24856812
属性
熔点 | 179-183°C |
溶解性 | Soluble in acetone, methanol, ethanol (10 mM), chloroform, and DMSO (100 mM). Insoluble in water. |
描述
应用 | Corticosteroid is an activator of MCR. |
生化机理 | Corticosterone is a hormone synthesized in response to stress. It binds and activates MCRs(mineralocorticoid receptors) and GRs (glucocorticoid receptors), which results in altered expression. This eventually affects ionic conductances through the membrane. Corticosterone induces apoptosis in murine bone marrow. |
别名 | 皮质酮;肾上腺酮;11β,21-Dihydroxy-4-pregnene-3,20-dione;11β,21-Dihydroxyprogesterone;4-Pregnene-11β,21-diol-3,20-dione;Kendall's Compound B;Reichstein's Substance H; |
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