Cation-Exchange Column for the Separation of Low-Molecular-Weight Species

The OmniPac^®PCX-100 column is a microporous, solvent-compatible, high-capacity, cation-exchange column designed for the separation of hydrophobic cations, such as amines, drugs, and metabolites.

• Acid, base, and solvent compatible, pH 0–14

• Good for organic cations

• Ideal for the separation of very hydrophobic cations

• Good for the separation of halogenated cations

The OmniPac PCX-100 column is a specialty cation-exchange column for the separation of low-molecular-weight cations, especially organic analytes. Group 1A and 2A inorganic cations are best separated on theIonPac CS12Acolumn, which is also solvent compatible. The OmniPac PCX-100 column is 100% solvent compatible and should always be run with at least 1% organic solvent in the mobile phase.

The OmniPac PCX-100 is manufactured using a microporous substrate agglomerated with a sulfonated latex bead layer that carries the cation-exchange functionality. The cation-exchange layer is the same as that used in the OmniPac PCX-500 column, and consequently the ion-exchange characteristics of these two columns are identical. The OmniPac PCX-100 column can be used to separate hydrophobic cationic analytes such as amines, anilines, antidepressants, drugs, and metabolites (such as methotrexate and folic acid).

Isocratic Separation of Aromatic Amines.

Separation of a Mixture of Inorganic Cations, Choline, and Acetylcholine by Two Different Chromatographic Modes.