Polymeric Reversed-Phase Column Ideal for the Separation of Hydrophobic, Ionizable Compounds

The IonPac^®NS1-10μm and NS1-5μm columns are packed with a neutral, macroporous, high-surface-area, ethylvinylbenzene polymer crosslinked with 55% divinylbenzene. This resin makes the NS1 resistant to solvents, acids, and bases, and permits the use of eluent from pH 0 to 14.

• Ideal for separation of large molecules that carry localized charges, such as surfactants

• Compatible with acids, bases, and solvent from pH 0 to 14

• Can also be used for traditional polymeric reversed-phase applications

• Utilize ion-pair chromatography for difficult separations

The IonPac NS1 column is the column of choice for routine ion-pair chromatography or ion-suppression separations using theAMMS^®ICE 300 suppressor. The NS1 is also used with mobile phase ion chromatography (MPIC^®), a technique especially suited to large molecules that carry localized charges (e.g., surfactants), as well as other ions that are not amenable to separation by ion-exchange chromatography.

Key Applications

The IonPac NS1 column can be used for the separation of high MW aliphatic carboxylic acids, alkyl and aromatic sulfates and sulfonates, quaternary ammonium ions, water-soluble vitamins, sulfur oxides, metal cyanide complexes, phenols, alkanolamines.

Separation of aliphatic sulfonic acids using tetrabutylammonium ion as the ion-pair reagent.

Determination of aliphatic quaternary ammonium ions using nonafluoropentanoate ion as the ion-pair reagent with an acetonitrile gradient.

Using the IonPac NS1 Column Determination of aliphatic carboxylic acids.

Separation of Alkanolamines on the IonPac NS1 Column Using Ion Pairing with Suppressed Conductivity Detection.