MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

L-4-Oxalysine hydrochloride

CAS No. : 118021-35-5

MCE 国际站：L-4-Oxalysine hydrochloride

产品活性：L-4-Oxalysine hydrochloride是从中国的链霉菌培养基中分离的天然物质，具有抗癌活性。

研究领域：Anti-infection

作用靶点：Fungal

In Vitro: Alpha-fetoprotein (AFP) is expressed in BEL-7404 human hepatoma cells and L-4-Oxalysine suppresses AFP mRNA expression in the cells. L-4-oxalysine functionally antagonizes the a-fetoprotein-induced suppression of the mitogen- and one-way mixed lymphocyte culture-induced proliferation of spleen lymphocytes and interleukin-6 production by these cells in mice bearing the hepatoma-22 tumor.

In Vivo: Tbe ultrastructural efects of different doses of L-4-Oxalysine on hepatocytes in mice are most serious at day 1 after stopping treatment. Mice are given ig L-4-oxalysine (I-677) 10, 50, and 100 mg/kg for 7 d. On day 8 the hepatocytes show accumulation of lipid droplets followed by loss of matrices in cytoplasm. The total area of lipid droplets is far less than 25% of mean section of hepatocytes. The injury of mitochondria and RER is only found in the groups of medium and high dose. L-4-oxalysine inhibits the proliferation of some mouse implanted tumors and pulmonary metastasis of mouse Lewis lung carcinoma.

相关产品：Antifungal agent 26  |  PC945  |  Proanthocyanidins  |  Chitin synthase inhibitor 11  |  Toyocamycin  |  Trifloxystrobin-d₃  |  Staurosporine  |  Phenazine-1-carboxylic acid  |  Ciclopirox olamine  |  Rubropunctamine  |  (+)-Columbianetin acetate  |  Aminothiazole  |  Amphotericin A  |  Griseofulvin-d₃  |  Sodium Houttuyfonate  |  Neticonazole  |  Chlordantoin  |  Bikaverin  |  Terconazole  |  Thiophanate-Methyl  |  1-Deacetylnimbolinin B  |  Antifungal agent 55  |  Valtrate hydrine B4  |  Pyrogallol  |  Antifungal agent 84  |  Trigonelline-d₃ chloride  |  Bulnesol  |  Anisocoumarin H  |  Trichodecenin II  |  Bifonazole

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物  |  寡核苷酸  |  抗体  |  点击化学

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides  |  Antibodies  |  Click Chemistry

品牌介绍:
•   MCE (MedChemExpress) 拥有200 多种全球独家化合物库，我们致力于为全球科研客户提供前沿最全的高品质小分子活性化合物；
•   50,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领；
•   产品种类涵盖各种重组蛋白，多肽，常用试剂盒 ，更有 PROTAC、ADC 等特色产品，广泛应用于新药研发、生命科学等科研项目；
•   提供虚拟筛选，离子通道筛选，代谢组学分析检测分析，药物筛选等专业技术服务；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；
•   专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。