MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务。
CAS No. : 6358-69-6
MCE 国际站:Pyranine
产品活性:Pyranine (HPTS; Solvent Green 7) 是一种 pH 敏感的荧光指示剂。Pyranine 是一类用于 Cu+ 离子的荧光化学传感器 (λex=450 nm,λem=510 nm)。
研究领域:Others
作用靶点:Fluorescent Dye
In Vitro: Pyranine is capable of discriminating ranges of cations from the Cu+ ion, even in competing environment. Pyranine displays a rapid fluorescence response (t1/2=1.66 min) towards the Cu+ ion, and the micromolar detection limit enables the detection of the ion in environmental samples. The observed stoichiometry of complexation between Pyranine and Cu+ is 2:1.
The pH-sensitive fluorescent indicator Pyranine is studied to determine its usefulness as probes for the living cornea and anterior chamber. Adequate concentrations are reached in the cornea and anterior chamber after topical administration; measurements can be made by fluorophotometry for many hours. The pH is calculated by measuring the ratio of fluorescent intensity at two excitation wavelengths, I463/I404, a measurement which is dependent on pH but independent of the concentration of the fluorophore and other variables which can alter the intensity. In the rabbit eye, Pyranine in the cornea and anterior chamber is observed to undergo easily measurable changes in fluorescent ratios associated with lid closure and contact lens wear, indicating its sensitivity to mild changes in pH.
相关产品:MeOSuc-Ala-Ala-Pro-Val-pNA | BDP 558/568 amine | AC-green | Naphthalene-1,2-dicarbaldehyde | Rhodamine 800 | Vari Fluor 532 SE | Acridine Orange hydrochloride | N-(7-Nitrobenzofurazan-4-yl)phallacidin | Biotin-11-UTP | BODIPY FL SSE | 1,2-Diamino-3,4-ethylenedioxybenzene | Sulfo-Cyanine5.5 NHS ester tripotassium | BODIPY 505/515 | 3-Acetylumbelliferyl β-D-Glucopyranoside | Ac-DNLD-AMC | Mucicarmine | 7-Aminocoumarin | NEP | Sulfo-cyanine3 azide sodium | Dihydrorhodamine 123 | Allophycocyanin | N-Acryloyl-1-pyrenebutylamine | TSPP tetrasodium | Dabcyl acid | 7-Diethylamino-4-methylcoumarin | 9-(2-Carboxy-2-cyanovinyl)julolidine | RT-NH2 | Coumberol | Carmoisine | 4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide
热门产品线:重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物 | 寡核苷酸 | 抗体 | 点击化学
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides | Antibodies | Click Chemistry
品牌介绍:
• MCE (MedChemExpress) 拥有200 多种全球独家化合物库,我们致力于为全球科研客户提供前沿最全的高品质小分子活性化合物;
• 50,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领;
• 产品种类涵盖各种重组蛋白,多肽,常用试剂盒 ,更有 PROTAC、ADC 等特色产品,广泛应用于新药研发、生命科学等科研项目;
• 提供虚拟筛选,离子通道筛选,代谢组学分析检测分析,药物筛选等专业技术服务;
• 设有专业的实验中心和严格的质控、验证体系;
• 提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告,确保产品的高纯度、高品质;
• 产品的生物活性多经各国客户实验验证;
• Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果;
• 专业团队跟踪最新的制药及生命科学研究进展,为您提供全球最新的活性化合物;
• 与世界各大制药公司及知名科研机构建立了长期的合作。