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CAS No. : 25301-02-4
MCE 国际站:Tyloxapol
产品活性:Tyloxapol (Triton WR1339) 是一种烷基芳基聚醚醇型非离子液体聚合物,用作表面活性稳定剂。Tyloxapol (Triton WR1339) 用于诱导动物高脂血症。
研究领域:Others
作用靶点:Biochemical Assay Reagents
In Vitro: Tyloxapol (100 μg/mL) triggers the detachment of HEK293 cells.
Tyloxapol induces nuclear fragmentation and the appearance of apoptotic nuclei.
Tyloxapol increases the risk of pulmonary haemorrhage, causes cytotoxicity in epithelial and red blood cells, and induces lysis of human Jurkat T-lymphoblasts.
In Vivo: Tyloxapol can be used in animal modeling to construct a rat model of hyperlipidemia.
Tyloxapol (Triton WR1339, 50 mg/kg) causes significant (P?< 0.05) decreases in the activities of the AChE and MAO enzymes in rat plasma and brain.
Tyloxapol leads to significant (P?< 0.05) reduction in the plasma urea, creatinine, and bilirubin.
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