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CAS No. : 24168-96-5
MCE 国际站:Isoconazole nitrate
产品活性:Isoconazole nitrate 是一种广谱的抗菌剂,具有强效的抗真菌和革兰氏阳性菌的活性,具有快速吸收和系统性暴露低的特性。
研究领域:Anti-infection
作用靶点:Bacterial | Fungal | Antibiotic
In Vitro: Isoconazole nitrate also exerts several other effects on the fungal membrane, which are independent of inhibition of the ergosterol synthesis. Isoconazole nitrate (ISN) causes a rapid reduction of cellular adenosine triphosphate (ATP) within 10 min of in vitro exposure.
Isoconazole nitrate (1, 10 μg/mL) induces a blockade of cell division in vitro by its action on synthesis and organisation of the cell membrane. Isoconazole nitrate (50, 100 μg/mL), ISN induced necrosis and death of fungal cells.
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