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Imiquimod hydrochloride

CAS No. : 99011-78-6

MCE 国际站：Imiquimod hydrochloride

产品活性：Imiquimod hydrochloride (R 837 hydrochloride) 是一种选择性的 toll 样受体 7 (TLR7) 激动剂，作为一种免疫反应调节剂。Imiquimod hydrochloride 在体内表现出抗病毒和抗肿瘤作用。Imiquimod hydrochloride 可用于外生殖器、肛周疣、癌症和 COVID-19 的研究。

研究领域：Immunology/Inflammation  |  Autophagy  |  Anti-infection

作用靶点：Toll-like Receptor (TLR)  |  Autophagy  |  SARS-CoV  |  HSV

In Vivo: In animal models, Imiquimod hydrochloride stimulates the innate immune response by increasing NK cell activity, activating macrophages to secretecytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod hydrochloride stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α.

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